🧠 AI Summary:
Some children with mitochondrial disease may also have autism, while others may only show a few overlapping symptoms—or none at all. This blog explains the relationship between autism and mitochondrial disorders in a simple, parent-friendly way. Although research is still developing, we break down what families need to know, what symptoms may appear together, and why every child’s profile is unique. On Target ABA is here to help families understand complex topics with clarity, compassion, and support.
Mitochondrial Disease & Autism: What Parents Should Know
When your child receives an autism diagnosis, it’s natural to explore what else might be contributing to their symptoms or behaviors. One question some families ask is:
“Is there a relationship between mitochondrial disease and autism?”
The answer is complex — but we’re here to explain it in a simple, supportive way.
What Are Mitochondria, and Why Do They Matter?
Mitochondria are tiny “energy factories” inside our cells. They help the body produce energy so muscles, organs, and tissues can work properly.
When the mitochondria don’t work the way they should, a child may experience things like fatigue, muscle weakness, or developmental differences. This is known as a mitochondrial disease.
Can a Child Have Both Mitochondrial Disease and Autism?
Yes — it’s possible, but it’s rare.
Here’s what research shows so far:
1. A child with a mitochondrial disease may also have autism.
Some children meet full criteria for autism spectrum disorder (ASD).
2. A child with mitochondrial disease may show some autism-like signs.
This may include things like differences in communication, challenges with social skills, or repetitive behaviors — but not enough for a full ASD diagnosis.
3. A child may have mitochondrial disease with no autism-related symptoms at all.
Every child’s presentation is unique.
What About Children With Autism? Do They Have Mitochondrial Disease?
Most children with autism do NOT have a mitochondrial disease.
But a small number may experience both conditions. When autism and mitochondrial disease occur together, children may also show additional medical challenges, such as:
- Epilepsy or seizures
- Low or high muscle tone
- Movement disorders
- Fatigue or muscle weakness
These symptoms vary significantly from child to child.
Is There a Strong Link Between Autism and Mitochondrial Disease?
Right now, the research is still evolving.
Here’s what we know:
- Having both conditions is uncommon.
- Some overlaps exist because both involve brain and body energy systems.
- Scientists still need more research to fully understand the connection.
Resources like Autism Speaks note that while interest in this topic is growing, the link is still considered rare and not fully understood.
What Parents Should Take Away
If your child has autism, it does not mean they have mitochondrial disease.
If your child has mitochondrial disease, it does not automatically mean autism will develop.
Each child’s medical and developmental profile is unique.
The best next step is always to:
- Work closely with your pediatrician
- Share any medical, developmental, or behavioral concerns
- Ask about genetic or metabolic testing if recommended
- Continue early intervention supports like ABA therapy
How On Target ABA Supports Families
At On Target ABA, we work with children across a wide range of developmental profiles. Whether your child has autism alone or autism with co-occurring medical conditions, our goal is the same:
To help them grow, communicate, and thrive in a way that honors their individual needs.
Families can learn more about our center-based services in:
Cleveland • Columbus • Worthington • Utah,
And here’s a trusted external resource for additional reading:
CDC Autism Overview → https://www.cdc.gov/autism
Final Thoughts
Autism and mitochondrial disease can occur together, but it is rare — and every child’s experience looks different. What matters most is having a supportive team, a clear plan, and therapies tailored to your child’s strengths.
On Target ABA is here to walk this journey with you.